TO EVALUATE THE USE AND SAFETY OF BLOOD THINNING AGENTS IN TERTIARY CARE HOSPITAL

Objective: To ensure the basic principles of drug utilization and the use and safety of blood thinning agents in tertiary care hospital. Experimental design: The study included 224 patients’ and was conducted in a tertiary care hospital and we were focused on to find out the drug-drug interactions of anticoagulants, antiplatelet, and thrombolytic agents, to study the major area involvement for blood thinning agents. The newly admitted case charts to the medicine ward will randomly be selected on a daily basis and will be reviewed for the medication safety compliance. Interpretation and Conclusion: Appropriate use of anticoagulant therapy and any deviation from the guidelines to a large extent also depends on patient characteristics and concomitant therapy patient is receiving. Some major complications are seen with oral anticoagulants which emphasize the need for a constant monitor and patient education. The need for dosage adjustments in different diagnostic situations or specific populations is very crucial. To increase patient education, an alert was built to notify pharmacists to educate patients on these new oral anticoagulants before discharge. Further studies from time to time are required in drug utilization pattern and standard treatment guidelines to be circulated among practicing physicians. The therapy with these drugs needs to be cost-effective and reduce the complications associated with their use.