TOPICAL APPLICATION OF BACTERIOPHAGES FOR THE TREATMENT OF WOUND INFECTIONS:

Wound infections persist as a significant and persistent challenge within the realm of healthcare, posing numerous detrimental consequences that extend far beyond the affected individuals. These infections, characterized by the infiltration of harmful microorganisms into wounds, encompass a multifaceted predicament that engenders slower healing periods, heightened morbidity rates, and an onerous financial burden on healthcare systems worldwide. Bacteriophages often known as phages, are viruses that selectively target and eradicate bacteria, making them a potentially effective alternative or supplementary treatment for wound infections. This article gives a general summary of what is currently known about using bacteriophages topically to treat wound infections. It goes through the fundamentals of phage treatment, looks at the benefits and drawbacks of phage use, examines the preclinical and clinical data that is now available, and identifies future research paths in this area. The review highlights the potential of bacteriophage-based therapeutics to transform the treatment of wound infections and provides information on the crucial factors to take into account for effective implementation.