UV-SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF TELMISARTAN IN BULK AND TABLET DOSAGE FORM
AbstractA simple, precise and accurate UV spectrophotometric method has been developed and validated for the estimation of Telmisartan in bulk and tablet dosage form. The spectra of Telmisartan in 0.1 N NaOH and distilled water (20:80) shows λmax at 234 nm and estimation was carried out by A (1% 1cm) and by comparison with standard. Calibration graph was found to be linear (r2= 0.999) over the concentration range of 2-10 μg/mL. The proposed method was validated for its accuracy, precision, specificity, ruggedness and robustness. The method can be adopted in its routine analysis.
Article Information
57
3936-3939
557KB
2069
English
Ijpsr
Sonali D. Rathod*, P.M. Patil, Santosh S.A. Waghmare and P.D. Chaudhari
Department of Pharmaceutical Chemistry, Modern College of Pharmacy, Nigdi Pune, Maharashtra, India
sonali_rathod15@yahoo.com
22 June, 2012
17 July, 2012
26 September, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(10).3936-39
01 October, 2012