UV-VISIBLE SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION OF ASSAY OF PARACETAMOL TABLET FORMULATION
AbstractA novel, safe and sensitive method of spectrophotometric estimation in UV-region has been developed for the assay of paracetamol in its tablet formulation. The method have been developed and validated for the assay of paracetamol using Methanol and water as diluents. Which does not shows any interference in spectrophotometric estimations. All the parameters of the analysis were chosen according to ICH [Q2 (R1)] guideline and validated statistically using RSD and %RSD along with neat chromate grams.
Article Information
56
4945-4953
896
11701
English
Ijpsr
Siladitya Behera*, Subhajit Ghanty, Fahad Ahmad, Saayak Santra and Sritoma Banerjee
Department of Quality Assurance and Pharma Regulatory Affairs, Gupta College of Technological Sciences, Ashram More, G.T. Road, Asanol-713301, District: Burdwan, West Bengal, India
siladitya.behera@gmail.com
10 August, 2012
28 September, 2012
29 November, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(12).4945-53
01 December, 2012