VALIDATION OF THE IAC YOKOHAMA SYSTEM FOR REPORTING BREAST FINE NEEDLE ASPIRATION CYTOLOGY AND HISTOPATHOLOGICAL CORELATION OF BREAST LESIONS IN VINDHYA REGION POPULATION

Background: Breast cancer is commonest malignancy of women globally. A palpable breast lump is common diagnostic dilemma to surgeons. In 2016,International Academy of Cytology (IAC) established a standardized approach for reporting Breast FNAC by categorizing the lesions in five tier system from C1 to C5 to standardize reporting, which will enhance Breast FNAB cytology performance, interpretation, and reporting and its histopathological correlation to improve diagnostic accuracy. Aims and Objectives: To categorize FNAC cases according to The IAC Yokohama System and correlate histopathologically (wherever possible) and evaluate the diagnostic ability of FNAC. Material and Methods: The current prospective analytical study was carried out in the Department of Pathology, Shyam Shah Medical College, Rewa, Madhya Pradesh, for a period of 15 months. The results were analysed based on cytological and histopathological reporting. Results: The highest number of cases were from the age group of 21- 30 years with 29% (n=29). The maximum number of cases, 69% (n=69) of the total, were found to be categorized under the category C2 (benign) which was followed by Category C5 (Malignant) seen in 13% (n=13). In the present study (2022) the sensitivity, specificity, PPV, NPV and accuracy of FNAC were 95%, 100%, 100%, 98.60% and 98.90% respectively (excluding premalignant cases). Conclusion: FNAC using IAC Yokohama system is a rapid and effective method for the primary categorization of palpable breast lumps and provides better clarity to the clinicians in the management of the patient and can reduce unnecessary surgeries.