RELATIVE EXPLORATION OF IN-VITRO ANTI- INFLAMMATORY ACTIVITIES OF DIFFERENT ARTOCARPUS SEED EXTRACTSAbstract
The study was undertaken to investigate and compare in vitro anti inflammatory activities of five varieties of hexane and methanol seed extracts each, specifically Artocarpus heterophyllus, Artocarpus integrifolia, Artocarpus hirsitus, Artocarpus inciscus and Artocarpus integer of Artocarpus species belonging to the family Moraceae by means of most prominent membrane stability assay. Results revealed that, the percentage of membrane stability exhibited by the test samples were concentration dependent and compared constructively with that of standard Diclofenac. Amongst two extracts methanolic seed extracts had highest percentage of inhibition and in both extracts Artocarpus integer had uppermost membrane stabilization capacity. The statistical analysis with student ‘t’ test showed significant difference for tested factors in between hexane and methanolic seed extract groups. The study disclosed that Artocarpus seed extracts could be seen as a potential natural source of membrane stabilizer and was capable of providing an alternative remedy for the management and source of membrane stabilizer and further studies were suggested to isolate the active principles responsible for the bustle.
Nagala Sirisha *, B. Archana, S. Brahmaji and T. Raghava Rao
Department of Biochemistry, College of Science and Technology, Andhra University, Visakhapatnam, Andhra Pradesh, India.
27 December, 2016
10 February, 2017
17 February, 2017
01 July, 2017