9.
Testicular toxicity has been associated with long-term paracetamol usage. Moringa oleifera is known to eliminate toxins from organs and restore functionality. This study seeks to ascertain the potency of moringa in ameliorating paracetamol-induced testicular toxicity. Forty nine (49) Sprague-Dawley rats were randomly assigned into seven (7) groups composed of 7 rats each treated for 5 weeks. One g...
O. A. Adebajo, J. H. Ojo, P. K. Adebajo, N. E. Bassey * and E. O. Olukoya
Department of Cell Biology and Genetics, Faculty of Science, University of Lagos, Nigeria.
DOI: 10.13040/IJPSR.0975-8232.15(5).1355-64
1355-1364
10.
Acetaminophen (APAP) is the most consumed potentially toxic drug in the world, and its cardiovascular injury has been emphasized. We evaluated the role of inflammatory mediators in the impaired vascular relaxation after APAP treatment. Rats were treated with APAP for 2 weeks (400 mg/Kg/day/p.o.) and after euthanasia, blood was collected for biochemical analysis (hepatic transaminases, lipid peroxi...
Hellen Karine Paes Porto, Mikaelle Costa Correia, Marcella Daruge Grando and Matheus Lavorenti Rocha *
Laboratory of Cardiovascular Pharmacology, Faculty of Pharmacy, Federal University of Goias, Goiânia/GO - Brazil.
DOI: 10.13040/IJPSR.0975-8232.15(5).1365-70
1365-1370
11.
Chenopodium album L., Chenopodium murale L., and Chenopodium giganteum L. are annual herbs with ethno-medicinal value. The present study investigates the primary and secondary metabolites quantification of Chenopodium species. The quantitative estimation of bioactive molecules from the root, stem, and leaves showed the presence of proteins, carbohydrates, starch, phenols, and flavonoids. However, ...
Hanuman Sahay Meena * and Rekha Vijayvergia
Department of Botany, University of Rajasthan, JLN Marg, Jaipur, Rajasthan, India.
DOI: 10.13040/IJPSR.0975-8232.15(5).1371-83
1371-1383
12.
Around the world, cancer frequently leads to death. Lung cancer is the primary cause of cancer-related deaths globally. Through in-silico analysis, this study sought to assess the anticancer effectiveness of myricetin on human lung cancer cells. The study's goal is to assess how well myricetin adheres to the Lipinski rule of 5. To evaluate the ADMET properties (Absorption, Distribution, Metaboli...
M. Viji, S. Aishwariya, C. Ireen, S. Hinduja, S. Indu, P. Vijayalakshmi and M. Rajalakshmi *
DBT-BIF Centre, Holy Cross College (Autonomous), Tiruchirappalli, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.15(5).1384-90
1384-1390
13.
Children under five years of age, with severe or cerebral malaria, cannot consume oral medication especially if they are vomiting or are unconscious. In such situations they are given an injectable drug until they can tolerate oral medication. The situation is bad in Sub-Saharan Africa, especially in rural areas as children are sometimes referred to the closest referral health care facility for pr...
E. K. G. Mhango, P. Marín, E. Escudero, M. T. Yuste, F. F. Eiriksson, B. S. Snorradottir, B. R. Sveinbjornsson and S. Gizurarson *
Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, 107 Reykjavik, Iceland.
DOI: 10.13040/IJPSR.0975-8232.15(5).1391-99
1391-1399