A REVIEW ARTICLES ON MUCOADHESIVE BUCCAL FILMS: A PROMISING APPROACH FOR ENHANCED DRUG DELIVERY
AbstractMucoadhesive buccal films have gained significant attention as a promising drug delivery system for various therapeutic applications. This review article provides a comprehensive overview of the recent advancements in mucoadhesive buccal films, focusing on their formulation strategies, mucoadhesive mechanisms and potential applications. The article discusses the various polymers used in the formulation of mucoadhesive buccal films, including natural, synthetic, and semi-synthetic polymers. The selection of appropriate polymers plays a crucial role in achieving optimal mucoadhesive properties and drug release characteristics. Furthermore, the influence of different formulation factors, such as plasticizers, penetration enhancers, and drug loading techniques, on the performance of buccal films is thoroughly examined. The discussion covers a wide range of topics, beginning with the structure and physiology of the buccal mucosa, which elucidates the particular properties that impact medication absorption. The complete examination of mucoadhesive polymers, nanoparticles, and thin film technologies is included in the comprehensive overview of formulation techniques.
Article Information
12
1661-1672
1688 KB
220
English
IJPSR
Abdallah Abdalmalk *, S. Rajarajan, Beny Abin and Vasudeva Rao
Department of Industrial Pharmacy, Faculty of Pharmacy, Karnataka College of Pharmacy, Karnataka, Bangalore, India.
abdallahabdalmalk@gmail.com
30 November 2023
11 February 2024
25 April 2024
10.13040/IJPSR.0975-8232.15(6).1661-72
01 June 2024
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