IN-VITRO EVALUATION OF ANTIOXIDANT AND HEPATOPROTECTIVE ACTIVITY OF AEGLE MARMELOS, LAWSONIA INNERMIS AND MURRAYA KOENGII

The present study was conducted with an objective to evaluate the in-vitro antioxidant and hepatoprotective activity of three different medicinal plants. Due to the adverse effects of therapeutic agent with better hepatoprotective activity in modern medicine several plants have been screened for the aforesaid activity during last few decades detailed literature survey revealed that leaves of Aegles marmelos, Lawsonia innermis and Murraya koenigii plants were traditionally used for their liver protective activity. When healthcare providers refer to liver disease, they’re usually referring to chronic conditions that do progressive damage to your liver over time. Chronic liver diseases are not uncommon worldwide and are characterized by progressive evolution from steatosis to chronic hepatitis, fibrosis, cirrhosis and hepatocellular carcinoma. There is growing evidence that free radicals and reactive oxygen species play an important role in the progression of liver diseases and thus plants with free radical scavenging activity could play a crucial role in preventing the progression of liver disorders. The results of the present study demonstrate that, all 3 plants which were selected based on their traditional and ethnomedical claim possess antioxidant activity, polyphenolic profiling and potential hepatoprotective efficacy. As a result, the study’s significant findings demonstrate that it is a step towards evidence-based phytomedicine.