PHYTOCHEMICAL AND ANTIOXIDANT STUDIES ON AN IMPORTANT INDIGENOUS MEDICINAL PLANT-ANDROGRAPHIS PANICULATA (BURM.F) NEES
AbstractAndrograhis paniculata is a wonder drug using in traditional systems of medicine for multiple clinical applications. This research article deals with the phytochemical and antioxidant properties of A. paniculata leaves. Qualitative and quantitative phytochemical analyses were carried out by TLC and HPLC method. Physico-chemical analysis was done to standardize the plant drug material so as to ensure the use of genuine material. The result of phytochemical studies confirmed the presence of various secondary metabolites like alkaloids, glycosides, flavonoids, proteins, tannins, phenols, saponins, terpenoids, quinones and steroids. TLC studies of chloroform extracts showed 3 spots and methanol extracts showed 5 spots at different Rf values. HPLC analysis confirmed the presence of the major active constituent andrographolide. Effect of age on quantity of andrographolide content was studied and it was found to be higher in 120 day old plants. Antioxidant property was determined by reducing power method. Maximum antioxidant activity was observed in pure andrographolide followed by methanol and water extracts of leaf powder
Article Information
21
5240-5244
604KB
2134
English
IJPSR
U. Umadevi and M. Kamalam
Department of Botany, PSGR Krishnammal College for Women, Coimbatore, Tamil Nadu, India
kamaluma12@gmail.com
30 April, 2014
18 July, 2014
08 August, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(12).5240-44
01 December 2014
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