OUR EXPERIENCE OF USING TOPICAL HAEMOCOAGULASE (BOTROCLOT) IN ARRESTING EAR, NOSE, THROAT AND HEAD AND NECK BLEED IN A TERTIARY CARE CENTER

Introduction: Topical haemocoagulase (Botroclot) is a fractionated snake venom extract which acts as procoagulant and augments healing. In our study we ascertain the various causes of bleeding in routine clinical practice and evaluate the efficacy of this agent in arresting minor bleeding. Aim and Objective: To ascertain the various causes of bleeding in routine ear, nose, throat (E.N.T.) practice in a tertiary care center and evaluate the efficacy of topical haemocoagulase in arresting minor E.N.T. and head and neck bleed. Materials and Methods: This study was conducted from October 2019 to April 2024 in the Department of Otorhinolaryngology. A total of 582 patients presenting with nasal, aural, oral cavity, oropharyngeal, laryngeal and head and neck bleed were included in this study. The cause of bleeding pertaining to individual subsites were identified and charted in tabulated format. Haemocoagulase solution was used for topical instillation over the bleeding site. Time taken from the application of solution to the cessation of bleeding was noted. Results: Amongst all the cases, Nasal bleed was the most common presentation (205 patients). Trauma was the most commonly encountered cause in almost all the subsite bleed. 291 (50%) cases showed spontaneous cessation of bleeding on application of topical haemocoagulase. In 262 (45%) cases bleeding stopped in less than 1 min and in 29 cases (5%) it took more than 1 minute to stop. Conclusion Application of topical haemocoaugulase fastens haemostasis, improves wound healing with no issues of rebound bleeding or any adverse effects even after multiple applications.