MOLECULAR DOCKING SIMULATION ON ISATIN- A MAGICAL MOLECULE
AbstractIsatin is magical molecule widely used in drug discovery of many areas like anticancer, anti-inflammatory, antiviral, anti-convulsant, anti-tubercular, antimicrobial, antidiabetic most important it was found effective in COVID-19 as well as on Lumpy Skin Diseases. Isatin can be synthesized by different methods like Sandmeyer method, Gassman synthesis. Isatin was modified by researchers at C2, C3, C5, position and contribute its magic into the medicinal field. In this research article, main focus has been done on design and docking of various derivatives possessing promising biological activity, novel drug design strategies and their respective drug target. It will provides different approaches to design new drug entity along with docking studies to the young researcher to dig new aspect of molecule.
Article Information
29
3652-3659
3874 KB
23
English
IJPSR
Dhanashri Dupade * and Anwar Shaikh
Allana College of Pharmacy, Azum Campus, Pune, Maharashtra, India.
dhanashri.dupadesvpm@gmail.com
12 July 2024
08 October 2024
25 October 2024
10.13040/IJPSR.0975-8232.15(12).3652-59
01 December 2024
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