PHYTOCHEMICAL ANALYSIS AND ANALGESIC ACTIVITY OF THE EXTRACT OF PROSOPIS JULIFLORA

Background: In dry and semi-arid regions of the world, Prosopis juliflora is one of the most significant tree species both commercially and environmentally. Leguminosae (Fabaceae) is the family to which Prosopis juliflora belongs. Aims and Objectives: To evaluate the analgesic activity of methanolic extract of dried leaves of Prosopis juliflora Linn. Materials and Methods: In this investigation, adult male Wistar rats weighing between 100 and 150 grams were utilized. Prosopis juliflora Linn. methanolic extract was given orally to healthy albino rats at dosages of 300 and 500 mg/kg body weight in order to assess the acute analgesic efficacy using the tail flick technique. Result: The methanolic extract demonstrated a substantial and dose-dependent reduction in the reaction time on tail-flick throughout the course of the 60 minutes in acute trials. Turkey’s test was performed after one-way ANOVA was used for statistical analysis. Conclusion: Methanolic extract of Prosopis juliflora Linn. possesses analgesic activity in a dose-dependent manner in thermal induced model.