GC-MS PROFILING OF BIOACTIVE COMPOUNDS IN ASPARAGUS RACEMOSUS: IMPLICATIONS FOR PHARMACOLOGICAL PROPERTIES

Background: Plants for remedial applications are well known, realizing the pharmacological potentials of plants through analytical techniques. Asparagus racemosus is a well-known medicinal plant analyzed using biological approach. The present study was carried out to evaluate the antioxidant, ani-inflammatory, antibacterial effects and the possible bioactive compounds present in the chloroform, methanol and aqueous extract of A. racemosus plant. Methods: The whole plant was subjected to serial solvent extraction using chloroform, methanol, and aqueous. Phytochemical screening, total phenolic and total flavonoid contents were determined using standard methods and was followed by GCMS and FTIR for biological activity of compounds. The plant extracts were assessed for antioxidant activity by DPPH and FRAP assays, anti-inflammatory activity by protein denaturation method, and antibacterial activity by agar well diffusion method. Results: The phytochemical tests revealed the presence of phytochemicals like alkaloids, flavonoids, glycosides, triterpenoids, and saponins. The GCMS of whole plant chloroform, methanol and aqueous extract revealed the compounds that are rich in free radical scavenging activity and proven to be the best source for antioxidant activity. The phenolics, flavonoids are linked with its antibacterial property. Conclusion: The present study helps to find out the novel bioactive compounds having pharmacological properties to formulate the safer drugs for the treatment of deadly diseases bothering mankind.