PHYTOCHEMICAL SCREENING STUDY AND CONSTIPATION ACTIVITY OF SPERMACOCE HISPIDA L. (RUBIACEAE) BY USING ALBINO RATS

The whole plant of Spermacoce hispida L is reported to have great medicinal value.It is found effective systemically in treating, headache, constipation, anti-hypertensive, anti-fertility, Appetite, Scabies, Irritant bowel syndrome and skin disease etc. Intake of 2 to 4 g of the seeds along with a mixture of dry ginger, coriander seed andfinger millet reduces the unwanted cholesterol namely LDL and HDL from the body. Traditionally roots, leaves and stem of the Spermacoce hispida L are used as anti-eczema, antibacterial and cardio-vascular disorder, etc. Recently it is found that this herb contains Calcium and Phosphorus in the abundance hence administration of this drug in form of chooranam or kudineer (decoction) is recommended in conditions like bone diseases, fractures etc The present investigation was therefore undertaken to evaluate the requisite phytochemical screening andthe constipation activity of Spermacoce hispida by using albino Wistar rats. Phytochemical analysis was carried out with different chemical reagents.Constipation activity of Spermacoce hispida   was analyzed by using albino Wistar rats.To cure the irritant bowel syndrome using the whole plant of hydro alcoholic extract instead of loperamide. These studies provided crucial information about the constipation activity of the whole plant hydro alcoholic extract. Further studies may be carried out to characterize and screen the valuable compounds present in the whole plant.