ANTIANEMIC ACTIVITY OF MAHUA FLOWER CONCENTRATE AND MAHUA LADDOO AGAINST 2,4-DINITROPHENYLHYDRAZINE INDUCED ANEMIA IN A RAT MODEL

Anaemia is a widespread problem that can be characterized by a decreased number of red blood cells and decreased haemoglobin levels. The aim of this study was to explore the antianaemic efficacy of mahua flower concentrate and mahua laddoo in comparison to the clinically prescribed iron tablet, Livogen XT, in an anaemic rat model. The anaemic rat model was developed by the administration of 2,4-dinitrophenylhydrazine. The antianaemic effects of mahua flower concentrate and mahua laddoo were evaluated by quantifying haematological limits, including haemoglobin contents, red blood cell count, and haematocrit. Additionally, proximate analysis was performed for the mahua flower concentrate and mahua laddoo. The proximate content of mahua concentrate and mahua laddoo exhibited good equilibrium of macronutrients, including carbohydrates and proteins, along with fat content, which contributes to their energy-providing properties. Orally, mahua concentrate and mahua laddoo were administered for a period of 23 days. The results revealed a significant increase in the haematological parameters in the treated groups compared with those in the negative control group. The use of mahua concentrate and mahua laddoo significantly increased the RBC count, haemoglobin level and haematocrit level. It is concluded that mahua flower concentrate and mahua laddoo are beneficial in the management of anaemia. Further studies are necessary to discover the fundamental molecular mechanisms involved and to confirm their clinical importance. The presence of mahua flower-based food products in the diet may suggest a promising alternative method to battling nutritional and drug-induced anaemia.