ISOLATION OF RUTIN FROM PHYLLANTHUS AMARUS
AbstractGeneral phytochemical screening of Phyllanthus amarus (Euphorbiaceae) revealed the presence of Saponin, tannins, glycoside and alkaloids etc. The aim of this study is to identify and characterize the bioactive principle from the plant. It has wide folk medicinal uses. The isolation and characterization of Phytoconstituents was done from the methanolic extract by the gradient fractionation method. The structure of the isolated compound was established on the basis of physical, chemical test and spectroscopic evidences (IR, UV, 1HNMR, MS). A flavonol structure was isolated from the methanolic extract of the plant. The odorless, colorless compound which solubilizes in methanol having m.p. 186oC and Rf value 0.46 in mobile phase Methanol: Glacial Acetic Acid: Water (90: 5: 5) was identified by the various spectroscopical methods. So from this study it is concluded that isolated compound may be rutin which is responsible for various pharmacological activities of the plant
Article Information
45
1198-1201
509KB
2081
English
IJPSR
Prabodh Shukla*, B. Gopalkrishna and Padmini Shukla
Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India
11 December, 2011
15 March, 2012
30 March, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(4).1198-01
01 April, 2012
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