ADVANCEMENTS IN ACNE VULGARIS TREATMENT: EXPLORING NANOEMULGEL DELIVERY SYSTEMS, CURRENT THERAPEUTICS, AND FUTURE PERSPECTIVES IN NANOPARTICLE-BASED APPROACHES

Acne vulgaris is a prevalent skin condition that affects millions globally, with significant physical, emotional, and social impacts. In spite of the accessibility of various therapeutic options, treatment efficacy remains limited due to issues such as drug resistance, side effects, and poor skin penetration. Recent advancements in nanotechnology have led to the development of innovative drug delivery systems, including nanoemulgel formulations, which offer enhanced therapeutic outcomes for Acne vulgaris. Nanoemulgels combine the benefits of both nanoemulsions and gel-based systems, providing improved skin penetration, sustained drug release, and targeted delivery to the affected areas. This review explores the mechanisms of Acne vulgaris, its pathophysiology, and the current therapeutic strategies, with a particular focus on nanoparticle-based treatments. The use of nanoparticles for drug delivery, especially in the form of nanoemulgels, offers promising solutions to the limitations of conventional treatments. This paper also discusses the sociological implications of acne, the challenges in patient compliance, and the future scope of nanoemulgel formulations in acne therapy. Finally, it highlights the potential of these advanced delivery systems in transforming the future of acne treatment, emphasizing their safety, efficacy, and prospects for clinical application in the years to come.