FORMULATION, STANDARDIZATION, PHARMACOLOGICAL INVESTIGATION OF THE ANTI-INFLAMMATORY POTENTIAL OF RASNA ERANDADI KWATH: AN IN-VITRO EXPERIMENTAL APPROACH

Inflammation is the body’s natural response to injury, infection, or tissue damage, characterized by redness, swelling, heat, pain, and functional changes. While conventional Anti-Inflammatory drugs are effective, their prolonged use can lead to adverse effects, prompting the search for safer, natural alternatives. Ayurvedic herbal decoctions like Rasna Erandadi Kwath, Sareevadi Kwatham, and Rasnadi Kwatham have demonstrated notable Anti-Inflammatory properties. These Kwaths are traditional water-based preparations made by boiling medicinal herbs to extract active phytochemicals. Rasna, Guduchi, and Devadaru are key ingredients known for their Anti-Inflammatory benefits. This study evaluates the Anti-Inflammatory potential of Rasna Erandadi Kwath at three concentrations-1:4 (Mrudu), 1:8 (Madhyam), and 1:16 (Kathin)-using In-vitro methods: BSA Protein Denaturation Assay and HRBC Membrane Stabilization Test. All three concentrations showed significant Anti-Inflammatory activity, with the 1:16 (Kathin) dilution showing the highest effect. These findings support Rasna Erandadi Kwath as a natural and holistic alternative to synthetic drugs for managing inflammation through Ayurvedic medicine.