STANDARDIZATION OF SIDDHA POLY HERBAL FORMULATION VILVATHY LEGIUM
AbstractThe standardization of Siddha formulations is a critical step for establishing consistent chemical profiles and ensuring quality control in the commercial manufacturing of herbal drugs. Vilvathy Legium is a Siddha polyherbal formulation in the Siddha Sastric textbook, Athmarakshamirtham Ennum Vaidhiya Sarasangiragam, authored by Kandhasamy Mudhaliyar and indicated for conditions such as gastrointestinal disorders and respiratory tract diseases. To ensure safety and therapeutic efficacy, the current study aimed to standardize Vilvathy Legium according to PLIM guidelines through organoleptic evaluation, physicochemical analysis, and safety testing. Safety assessments confirmed that heavy metals (Pb, Hg, As, Cd), microbial loads, and mycotoxins were well within permissible limits, while all targeted pesticide residues were below the limit of quantification. Preliminary HPTLC fingerprinting at 254 nm, 366 nm, and 580 nm identified distinct chemical peaks for phenolics, flavonoids, and saponins. This study provides quality-indicating physiochemical and chemical fingerprints necessary for the routine quality assurance of Vilvathy Legium.
Article Information
15
2415-2426
1123 KB
8
English
IJPSR
A. Divya *, V. Priyadharshini, P. Arul Mozhi and M. Meenakshisundaram
Department of Kuzhandhai Maruthuvam, National Institute of Siddha, The Tamil Nadu Dr. M.G.R Medical University, Chennai, Tamil Nadu, India.
divyabsms05@gmail.com
06 April 2026
04 June 2026
19 June 2026
10.13040/IJPSR.0975-8232.17(8).2415-26
01 August 2026
Download