TASTE MASKING BY ION EXCHANGE RESIN AND ITS NEW APPLICATIONS: A REVIEW
AbstractMore than 50% of pharmaceutical products are orally administered for several Reasons and undesirable taste is one of the important formulation problems that is Encountered with such oral products. Taste of a pharmaceutical product is an important parameter governing compliance. Hence taste masking of oral Pharmaceuticals has become important tool to improve patient compliance and the Quality of treatment especially in paediatrics. Different methods have been suggested for Masking of taste of bitter drugs, which includes, coating of drug particles with inert agents, taste masking by formation of inclusion complexes, molecular complexes of drug with other chemicals, solid dispersion system, microencapsulation, multiple emulsions, using liposome’s, Prodrugs and mass extrusion method but ion exchange resin is one of most extensively Used method to overcome this problem. Ion-exchange resins (IER) have received considerable attention from pharmaceutical scientists because of their versatile properties as drug-delivery vehicles. In the past few years, IER have been extensively studied in the development of novel drug-delivery systems (DDSs) and other biomedical applications. Also Recently the New Applications of Ion Exchange Resin like Opthalmic Drug Delivery, Anti-Deliquescence, Improve Solubility, and Polymorphism has confirmed. This review highlights complete account of ion exchange resin and its application in drug delivery research are-discussed.
Article Information
2
22-37
441 kB
4725
English
IJPSR
V. K. Suhagiya*, A. N. Goyani and R. N. Gupta
Department of Pharmaceutical Sciences,Birla Institute of Technology, Mesra, Ranchi (Jharkhand), India
vishusuhagiya@gmail.com
10 February, 2010
20 March, 2010
25 March, 2010
http://dx.doi.org/10.13040/IJPSR.0975-8232.1(4).22-37
01 April, 2010