METHODS FOR DETERMINATION OF ANTIOXIDANT CAPACITY: A REVIEW
AbstractAntioxidants have become a vital part of our lives today. Antioxidants help neutralize or destroy “Reactive Oxygen Species” (ROS) or free radicals before they can damage cells. This paper focuses on types of damaging free radicals generated in metabolic processes and also gives an insight of mechanistic aspect of various in-vitro methods for evaluation of antioxidant capacity of plant metabolites and dietary supplements. The various HAT based, ET based assays and cellular antioxidant capacity assay (CAA) are discussed here. The oxidation induced by Reactive oxygen species (ROS) may result in cell membrane disintegration, membrane protein damage and DNA mutations which play an important role in aging and can further initiate or propagate the development of many diseases, such as arteriosclerosis, cancer, diabetes mellitus, liver injury, inflammation, skin damages, coronary heart diseases and arthritis
Article Information
6
546-566
821KB
15632
English
Ijpsr
Deepshikha Gupta
Department of Chemistry, Amity Institute of Applied Sciences, Amity University Uttar Pradesh, Sector 125, Noida-20130, India
deep_shikha_1999@yahoo.com
26 May, 2014
10 August, 2014
13 October, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).546-66
01 February, 2015
Download