EVALUATION OF ANTI-TUSSIVE ACTIVITY OF ROSA CENTIFOLIA
AbstractAim of study is to evaluate the potential anti-tussive activity in a mouse model induced by sulphur dioxide gas of ethanolic extract of “Rosa centifolia”. The ethanol extract of Rosa centifolia (250mg/kg 500 mg/g p.o) showed significant anti-tussive activity, the cough inhibition (35% and 57% respectively) and being comparable to that of 10-20mg/kg of codeine phosphate (41 and 64% respectively).The effect of ethanolic extract on the trachea was also tested it did not relax pre-contractions in guinea pig trachealis induced by KCl and histamine
Article Information
20
1473-1475
495
1206
English
Ijpsr
R. Anand Sankar*, C. Nikhila , V. C. Lakshmiprasanna , S. K. Mobeena, K. Karunakar and N. Bharathi
Asst. Prof., Jagan, s College of pharmacy, Department of Pharmacology, Jangalakandrika, Nellore, Andhra Pradesh, India
27 February, 2011
25 March, 2011
08 May, 2011
http://dx.doi.org/10.13040/IJPSR.0975-8232.2(6).1473-75
01 June, 2011
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