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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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SYNTHESIS, SPECTROSCOPIC, THERMAL STUDIES AND BIOLOGICAL ACTIVITY OF A NEW SULFAMETHOXAZOLE SCHIFF BASE AND ITS COPPER COMPLEXES

Abstract

A new Sulfamethoxazole Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzenesulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated on the basis of Physiochemical methods. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The IR spectra suggest that the ligand act as tridentate (from oxygen and two nitrogen atoms) donor. Also the biological activity of the Schiff base and its Cu complex were studied.

Article Information

15

3143-3148

1042

1602

25

English

Ijpsr

M. A. El-Nawawy, R. S. Farag, I. A. Sabbah, and A. M. Abu-Yamin*

Department of Chemistry, Faculty of Science Al-Azhar University, Cairo, Egypt

05 August, 2011

17 October, 2011

10 November, 2011

://dx.doi.org/10.13040/IJPSR.0975-8232.2(12).3143-48

01 December, 2011

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