ANALGESIC AND ANTIDIARRHOEAL ACTIVITIES OF LAWSONIA INERMIS
AbstractThe leaf of the plant Lawsonia inermis was examined for analgesic and anti-diarrhoeal properties. From the study of analgesic activity it was found that ethanol extract at a dose of 500 mg/kg exhibited no significant (p<0.3) inhibition of writhing reflex (28.45 % inhibition) while the inhibition of standard drug diclofenac sodium showed 82.7 % inhibition at a dose of 25 mg/kg body weight. The findings suggested that the leaf extract of Lawsonia inermis possessed anti-diarrhoeal activity at the dose of 500 mg/kg body weight compared to the control group and offered about 1.398 of the mean latent period for diarrhoeal episode to ensue and the result was significant (P<0.002).
Article Information
23
3183-3188
591
1033
English
Ijpsr
Saki Sultana * and K. Hasan Khosru
Lecturer, Department of Pharmacy, BRAC University, Dhaka-1212, Bangladesh
28 July, 2011
16 October, 2011
10 November, 2011
http://dx.doi.org/10.13040/IJPSR.0975-8232.2(12).3183-88
01 December, 2011
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