SYNTHESIS AND ANALYTICAL METHOD DEVELOPMENT OF A NEW PRODRUG OF ACECLOFENAC
AbstractIn the present work, a prodrug (2) of aceclofenac was synthesized using N-hydroxymethylisatin (1) as promoiety. Its structure was established on the basis of modern analytical techniques. An analytical, rapid, cost-effective and accurate method using UV-spectroscopy has been developed for the synthesized prodrug. The results and calibration curves obtained with different solvents for the prodrug revealed that the method developed was precise and accurate
Article Information
25
3872-76
333
1247
English
Ijpsr
Niti Bhardwaj, P. Ahuja , Farah Iram and Asif Husain *
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India
drasifhusain@yahoo.com
19 February, 2015
24 April, 2015
05 June, 2015
DOI: 10.13040/IJPSR.0975-8232.6(9).3872-76
01 September, 2015