DERMATOPHYTOSIS: INFECTION AND PREVENTION -A REVIEW
AbstractThe growing impact of infections caused by dermatophytes i.e. Trichophyton, Microsporum and Epidermophyton is not upto the mark in their treatments via conventional methods due to resistance, side effects, and high toxicity. Over prescription and overuse of traditional antifungal agents, high side effects, less eco-friendly nature, high manufacturing costs, high management costs etc., have stimulated the research for alternative natural drugs, such as herbal extract, essential oils and some commercially available compounds. This paper reviews the antidermatophytic activity of various commercially available and conventionally available herbals from different plants and their major role in prevention of prevalent strains dermatophytes. The mode of action of dermatophytes for causing dermatophytosis as well as mode and mechanism of action of various antifungal agents (herbals extracts, oils, suspensions and commercially available compounds) have also proposed. In vitro susceptibility tests and in vivo models used in antidermatophytic assays as well as the mechanism of action of dermatophytes are involved under the perspective of the potential use of herbals as antifungal agents in the clinical treatment of resistance strains responsible for dermatophytosis
Article Information
6
3218-25
409
2289
English
IJPSR
R. Kumar, S. K. Shukla, A. Pandey, H. Pandey, A. Pathak and A. Dikshit *
Biological Product Laboratory, Botany Department, Faculty of Science, University of Allahabad, Allahabad, Uttar Pradesh, India
anupambplau@rediffmail.com
27 March, 2016
01 July, 2016
05 July, 2016
10.13040/IJPSR.0975-8232.7(8).3218-25
01 August 2016
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