ANTICANCER ACTIVITY OF CALOPHYLLUM INOPHYLLUM L., ETHANOLIC LEAF EXTRACT IN MCF HUMAN BREAST CELL LINES
AbstractCancer is a major health problem; almost thought – out the world. Herbal medicines have a vital role in the prevention and treatment of cancer. The present study, the in vitro anticancer activity of Calophyllum inophyllum ethanolic leaf extract was evaluated in MCF-7 Breast cancer cell lines. Anticancer activity was evaluated with MTT standard colorimetric assay against MCF-7 cells with IC50 value of 120µg/mL. The biologically active metabolites were identified and quantified by a GC-MS method shows presence of 11 different bioactive compounds. The cytotoxic effect was found to be concentration dependent. Increased concentration of the leaf extract showed increased cytotoxicity
Article Information
18
3330-35
471
1646
English
IJPSR
K. Jaikumar, Sheik Noor Mohamed M., Anand D and P. Saravanan *
Department of Botany, Ramakrishna Mission Vivekananda College, Mylapore, Chennai, Tamilnadu, India
sarviveka@gmail.com
22 March, 2016
24 May, 2016
13 July, 2016
10.13040/IJPSR.0975-8232.7(8).3330-35
01 August 2016
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