THROMBOLYTIC POTENTIAL OF PUNICA GRANATUM – A STUDY IN THE RAT MODEL
AbstractAlthough the antioxidant and thrombolytic potential of the “super fruit” pomegranate has been well established and documented in in vitro models, its efficacy in an animal model has not been recognised. Therefore in the present study, the aril and rind of Punica granatum were scrutinized for their role in clot lysing competence in a thrombus induced rat model. Visual manifestation, coagulation time parameters and the level of the thrombotic factors confirmed the thrombolysis. The extracts were compared with the standard drug streptokinase that was administered in rats
Article Information
20
3348-54
410
1449
English
IJPSR
Shalini H. Kumar and A. Pushpa *
Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India
pushpa.biochem@gmail.com
28 March, 2016
24 May, 2016
30 June, 2016
10.13040/IJPSR.0975-8232.7(8).3348-54
01 August 2016
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