SEPARATION AND CHARACTERIZATION OF TRITERPENE COMPOUND EUPHOL FROM THE LEAVES OF AZIMA TETRACANTHA
AbstractAzima tetracantha is a small flowering shrub belongs to salvadoraceae family and commonly known as mulluchangu or mulsangu in Tamil. It is an best known medicinal plant ,which have a central role in the treatment of disease from pre historical period. From the plant lot of phytochemicals has been reported such as alkaloids, steroids ,tannins, terpenoids, flavonoids, glycosides, phenols etc and also possesses activities such as antioxidant, antifungal, antibacterial , hepatoprotective, antidiabetic and antihyperlipidemic etc .In the present study preliminary evaluation and isolation of an active pharmacological compound euphol was obtained from the chloroform extract of the leaves of Azima tetracantha was carried out. The compound euphol is a tetracyclic triterpene alcohol which produces antinociceptive effects in inflammatory and neuropathic pain. The compound was isolated by column chromatography and characterized by chemical test, TLC, FTIR, NMR, C 13 NMR spectrum. In future it may be a promising molecule for the management of neuropathic pain
Article Information
29
3423-27
383
1338
English
IJPSR
C. Kavitha * and V. Sandhiya
Department of Pharmacognosy, C.L. Baid Metha College of Pharmacy, Chennai, Tamil nadu, India
kavithacmpharm@gmail.com
04 March, 2016
12 April, 2016
04 May, 2016
10.13040/IJPSR.0975-8232.7(7).3423-27
01 August 2016
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