ANTIHAEMOLYTIC ACTIVITY OF PHYTOCHEMICAL AQUEOUS EXTRACTS OF PTEROCARPUS SANTALINUS AND PHYLLANTHUS EMBLICA IN RED BLOOD CELLS OF HUMAN SUBJECTS RECEIVING CHRONIC ALCOHOL AND CIGARETTE SMOKING
AbstractMedicinal plants are natural gift to human lives to promote disease free healthy life. Worldwide believe that herbal remedies are safer and less damaging to the human body than synthetic drugs. The heartwood of Pterocarpussantalinus (PSB) and the fruit of Phyllanthusemblica (PEF) are important medicinal parts with several ethnomedicinal properties. Keeping in view their importance, this work was carried out to investigate the qualitative, quantitative determination of crude phytocompounds and their effect on ethanol-induced haemolysis in human subjects. The phytochemical screening revealed the presence of some important active ingredients. In vitro studies showed that aqueous extracts of PEF and PSB possesses antioxidant as well reduced hemolytic activity on different subjects were found in the following order Smokers > alcoholic smokers > alcoholics. Our data shows that the active compounds present in PSW and PEF may offer protection against free radical mediated oxidative stress in RBC of humans with ethanol – induced haemolysis
Article Information
39
3857-64
460
1321
English
IJPSR
T. Lokesh, B. Sarada , K. Swarnalatha , M Abdul Kareem, N.CH. Varadacharyulu *
Department of Biochemistry, Sri Krishnadevaraya University, Anantapuramu, AP, India
nchvaradacharyulu@yahoo.com
21 April, 2016
03 June, 2016
29 June, 2016
10.13040/IJPSR.0975-8232.7(9).3857-64
01 September 2016
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