MODULATION OF 10 GHZ MICROWAVES INDUCED BIOCHEMICAL CHANGES IN DIFFERENT ORGANS OF SWISS ALBINO MICE BY PRUNUS DOMESTICA FRUIT EXTRACT

For the present study thirty male Swiss albino mice were selected from an inbred colony. They were divided into three groups consisting of ten mice in each group. Group I: Sham exposed, Group II: 10 GHz MW (microwave) exposed, Group III: PDE (Prunus domestica extract) +MW exposed. After 30 days of treatment the animals were sacrificed to study alterations in body weights and biochemical parameters in different organs of Swiss albino mice viz. intestine, liver, testis and spleen. MW exposure did not resulted in significant reduction in body weights compared to sham exposed group of mice. PDE supplementation prior MW exposure did not result in any significant weight gain compared to MW exposed group.  Biochemical analysis showed highly significant (p<0.001) variations in Lipid Per Oxidation (LPO), Glutathione (GSH) and protein levels which could be ameliorated by supplementation of PDE prior to MW exposure. Exposure to 10 GHz leads to biochemical alterations in different organs studied in mice which can be ameliorated by PDE supplementation. It can be concluded from the current study that exposure to microwave radiation caused significant alterations in the LPO, GSH and protein content of different organs of Swiss albino mice and supplementation of PDE prior microwave exposure repaired the damage to an extent.