TOTAL PHENOLIC CONTENT AND ANTIOXIDANT POTENTIAL OF CUCURBITA MAXIMA (PUMPKIN) POWDER
AbstractAs Antioxidant potential of many plants is mainly due to phenolic components such as phenolic acid, phenolic diterpense therefore total phenolic content and antioxidant potential of cucurbita maxima. (Pumpkin) powder was determined respectively by using Folin-Ciocalteu reagent and diphenyl-picryl-hydrazyl (DPPH) assay. In this method the antioxidants present in the plant extracts reacted with DPPH, which is a stable free radical and converted it to 1,1-diphenyl-1,2-picryl, hydrazine. Total phenolic content of pumpkin was determined using Folin-Ciocalteu reagent and gallic acid as standard, amount of phenolic compound was found to be 6.5 mg/gm powder of the drug. The high fiber content of pumpkin helps to aid proper digestion and in traditional medicine it is used as an anthelmintic, taenicide, diuretics and in the treatment of hemorrhoids so we compared the anti oxidant potential of pumpkin powder with marketed preparation (Pilex tablet). The half maximal inhibitory concentration (IC50) is a measure of the effectiveness of a compound in inhibiting biological or biochemical function. IC50 value of pilex tablet = 8.53 µg/ml & IC50 value of pumpkin powder =9.12 µg/ml.
Article Information
36
1903-1907
453KB
4062
English
IJPSR
Bansode Ashwini Sopan*, Devhadrao Nitin Vasantrao and S. Bansode Ajit
Department of Quality Assurance, VJSM’S Vishal Institute of Pharmaceutical Education & Research Ale, Junnar, (Pune) 412409 Maharashtra, India.
ashwini.bansode2@gmail.com
09 December, 2013
15 January, 2014
09 March, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1903-07
01, May 2014
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