BACTERICIDAL SCREENING AND ESTIMATION OF FREE RADICAL SCAVENGING ACTIVITY OF FRUTICOSE LICHEN CLADONIA SCABRIUSCULA DELISE (NYL.) FROM GOPESHWAR, UTTARAKHAND, INDIA
AbstractLichens came as a consortium of two distinct and dissimilar components- the mycobiont and the phycobionts, which were defined as a composite organism. Lichen vegetation in India is dominated by more than 2500 species. Lichen secondary metabolites specially the phenolics, depsides and depsidones are unique in their origin and are found nowhere else. Much attention has been paid on the biological roles of lichen secondary substances in the recent past; which have been found to possess a lot of bioactivities, such as anti-tumor, antibacterial, antifungal, antiviral, anti-inflammatory and antioxidant activities. The present study aims on the bactericidal activity of lichen, Cladonia scabriuscula, collected from the Gopeshwar, Uttarakhand in the Western Himalayas. The 50% v/v ethanolic extract (CSE) extracted through cold extraction method was tested for its bactericidal potential against prevalent water borne pathogen and its antioxidant potential through CLSI protocol. The CSE was found active against E. coli and S. typhimurium with MIC 2.48 and 1.02 mg/ml respectively; while the FRSA IC50 was 0.625 mg/ml.
Article Information
27
2847-2851
387
1006
English
IJPSR
A. Pandey *, A. Qidwai, M. Pandey, R. Kumar, S. K. Shukla and A. Dikshit
Biological Product Lab, Department of Botany, University of Allahabad, Allahabad, Uttar Pradesh, India.
deep.7890@gmail.com
28 September, 2017
01 June, 2018
07 June, 2018
10.13040/IJPSR.0975-8232.9(7).2847-51
01 July, 2018
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