GASTRIC ULCER PROTECTIVE EFFECT OF MADHUCA LATIFOLIA ROXB BARK IN WISTAR RATS
AbstractThe present study was carried out to investigate the protective effect of ethanolic extract of Madhuca latifolia (Roxb.) bark (MLE) and aqueous extract of Madhuca latifolia (Roxb.) bark (MLA) in aspirin-induced gastric ulcer. In both extract, acute toxicity performed according to guidelines for the selection of doses. The oral administration (400 mg/kg) of MLE & MLA extract reduced the ulcer index and prevents the development of gastric lesions by 76.57% and 81.14% (% of protection), respectively. The present studies provide preliminary data on the antiulcer potential of bark and support the traditional uses of the plant for the treatment of gastric ulcer.
Article Information
68
4051-4055
640
1236
English
IJPSR
N. Patel, P. Kumar *, S. Rai, M. P. Singh, R. Pandey, S. S. Shukla, S. Saraf, S. Patel and D. Patel
KIET School of Pharmacy KIET Group of Institutions, Ghaziabad, Uttar Pradesh, India.
puspendrapatel9@gmail.com
23 March 2014
13 June 2014
28 June 2014
10.13040/IJPSR.0975-8232.5(9).4051-55
01 September 2014
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