HEPATOPROTECTIVE POTENTIAL OF YOUNG LEAVES OF TRITICUM AESTIVUM LINN. AGAINST CCl4 INDUCED HEPATOTOXICITY
AbstractThe plant selected for the activity is obtained from the ninth day young leaves of Triticum aestivum Linn. belonging to the family Poaceae. The plant is commonly known as Wheatgrass which is used for various medicinal and health benefits for many years. It is considered as a cleansing and purifying agent from ancient times and yet can be used for its healing properties because of its nutritional values. The leaves contain many chemical compositions such as proteins, flavonoids, alkaloids, glycosides, terpenoids, saponins, fibers, tannins, and phenolic compounds. Wheatgrass is also rich in chlorophyll which consists of Chlorophyllin (derivatives of chlorophyll) and posses bacteriostatic and antioxidant properties. The concentrated methanolic extract showed significant hepatoprotective effect at 500 mg/kg dose in carbon tetrachloride (CCl4) treated rats. The blood samples were collected, and the serum was estimated for biochemical parameters SGOT, SGPT, alkaline phosphatase, total and direct bilirubin content. The studies indicated that the recovery of liver from CCl4 damage after the treatment was significant.
Download