THE NOVEL CORONA VIRUS (nCoV2) SEEMS TO DEFY ALL LAWS OF VIROLOGY

Amongst the known coronaviruses, many were responsible for causing disease in humans knowingly from the common cold to acute severe respiratory syndrome. The novel coronavirus, nCoV-2 has been implied to cause increasingly severe damage to public health besides demolishing the global economy with a staggering figure of continuous rise in mortality within the afflicted cases in almost every country on this planet. Owing to the perplexed scenario there are growing challenges involved in the containment of the spread of this novel coronavirus, which is mounting to be numerous and continuous. The battle is still on with this nCoV-2 since it has evolved, presenting with initial flu symptoms in patients affected to atypical pneumonia mimicking a catastrophic disseminated intravascular coagulation stage leading to cardio-respiratory abnormalities thus assuming proportions of mysterious illness to very unusual symptoms encountered in different age groups. The genomic analysis of the nCoV-2 has revealed constant potential mutations with the evolution of different strains, thereby posing numerous challenges to develop an effective vaccine that will hold a promise on providing long term immunity to the host. This review critically analyzes its arrival and spread across the globe to almost entire virology of this novel coronavirus to challenges that might be encountered in the future even if the vaccine is ready to combat the virus.