PHYSICOCHEMICAL STUDY AND DEVELOPMENT OF SOPs OF A POLYHERBAL UNANI FORMULATION: SAFŪF-I MU’ALLIF

In the Unani system of medicine, different dosage forms of the drug are used; out of them powder dosage form is known as Safūf, which is an important dosage form and has been used frequently since long. There are many Unani preparations used in the form of Safūf to treat various diseases. Safūf –I Mu’allif (SM) is a polyherbal Unani formulation that is known to be used as Spermatogenic agent and semen thickening agent. The drug is also used to treat sexual disorders like premature ejaculation, nocturnal emission, sexual debility, etc. Physicochemical study and development of standard operating procedures (SOPs) of polyherbal Unani formulations are essential to assess the quality, purity, and efficacy and consistency of drugs. The study formulation consists of following ingredients Tāl Makhānā (Asteracantha longifolia Nees.), Sā’lab Miṣri (Orchis latiflolia L.), Singhārā Khushk (Trapa bispinosa Roxb.), Gond Kīkar (Acacia Arabica Willd.), Māzu Sabz (Quercus infectoria Oliv.), Maṣṭagi Rumi (Pistacia lentiscus L.), Nishāshtah Gandum (Triticum aestivum L), Shaker Sūfed (Saccharum officinarum L.). The main aim of this study was to standardize the formulation on widely accepted physicochemical parameters and also develop the standard operating procedures (SOPs) for the preparation of the formulation scientifically.