RATIONAL APPROACHES FOR SYNTHESIS OF SOME NOVEL IMIDAZOLE HETEROCYCLES WITH THEIR BROAD SPECTRUM OF PHARMACOLOGICAL ACTIVITIES: A BRIEF REVIEW
AbstractImidazole has a special role in heterocyclic chemistry, and its derivatives have piqued interest in recent years due to its diverse chemistry and pharmacology properties. Imidazole is a nitrogen-containing heterocyclic ring that is essential in biology and pharmaceuticals. As a result, imidazole compounds have piqued the attention of researchers for more than a decade. Thus imidazole compounds have been an interesting source for researchers for more than a century. Antibacterial, anticancer, anti-tubercular, anti-fungal, analgesic, and anti-HIV activities are among the biological activities of imidazole derivatives. This paper aims to look back on the biological activities of imidazole over the years. A large number of imidazole derivatives are available. The incorporation of the imidazole nucleus is an important synthetic Strategy in drug discovery. The high therapeutic properties of imidazole-related drugs have prompted medicinal chemists to develop a slew of new chemotherapeutic agents. In clinical medicine, imidazole medications have a broader application in treating a variety of conditions. Imidazole can be synthesized using a variety of methods.
Article Information
6
1079-1085
781 KB
664
English
IJPSR
Nilesh S. Pendbhaje *, Rutuja D. Bankar, Abolee S. Bramhankar, Rupali V. Nirmal and Ashwini A. Jamdhade
Head of Department, Diploma in Pharmacy, SRE’S, Sanjivani College of Pharmaceutical Education and Research, Kopargaon, Maharashtra, India.
nileshpendbhajedpharm@sanjivani.org.in
10 May 2021
02 July 2021
05 July 2021
10.13040/IJPSR.0975-8232.13(3).1079-85
01 March 2022
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