ANTIOXIDANT EFFICACY OF GARLIC DERIVED ALLICIN ON CULTURED BREAST CANCER CELL LINES
AbstractThe present study aims at analyzing the efficiency of allicin, agarlic derived phytochemical or neutraceutical in elevating the activities of various enzymic antioxidants on its treatment to cultured breast cancer cell lines. In the experimental work, cultured breast cancer cell lines were treated with different doses of allicin, and through standardized protocols, the cell lines were assayed for the activities of enzymic antioxidants such as Peroxidase, Superoxide dismutase, Catalase and Glutathione S Transferase as compared to untreated control. It was found that allicin treatment significantly increased the activities of the said enzymic antioxidants as compared to control. This study demonstrates the antioxidant potential of allicin in cancer cells, showing decreased antioxidant activity as a characteristic feature of cancer cells, leading to severe oxidation-induced damage. The study also proposes future prospects in the areas of cancer research and therapy to cobble for the designing of targeted plant-based therapies that are easily available and are cost effective in comparison to synthetic therapeutic chemicals and that too without side effects.
Article Information
34
1322-1331
632 KB
397
English
IJPSR
Anubha Chaudhari * and Rajendra Chauhan
Department of Zoology, Government MLB Girls PG Autonomous College, Bhopal, Madhya Pradesh, India.
anubha88chaudhari@gmail.com
03 June 2021
27 July 2021
28 July 2021
10.13040/IJPSR.0975-8232.13(3).1322-31
01 March 2022
Download