HEAVY METAL CONTENTS AND ASSOCIATED HEALTH RISK OF SOME GHANAIAN AND ASIAN HERBAL DRUGS
AbstractThis study looked at heavy metal levels in selected registered herbal drugs of Asian and unregistered Ghanaian herbal drugs sold in Kumasi. It examined the health risks of the metals. It provided authorities with data to ensure that herbal drugs are strictly monitored and their metal levels evaluated to safeguard patrons’ health. Dry ashing method was used on 10g of each of the herbal drug samples. Ashes were digested at 95 ºC with 70% HNO3 and 70% HClO4 (2:5v/v), and then metals were analyzed using Atomic Absorption Spectrophotometer (AAS). The Asian drugs recorded 27.42E-01 mg/kg (Fe), 28.17E-0 4 mg/kg (Pb), 27.43E-0 4 mg/kg, 12.06E-06E-0 2 mg/kg (As) and 79.72E-0 2 mg/kg (Cu) whilst the Ghanaian drugs recorded mean levels of 15.43E-01 mg/kg (Fe), 24.99E-02 mg/kg (Pb), 16.04E-03 mg/kg, 47.70E-0 4 mg/kg (AS) and 12.37E-0 4 mg/kg. Metal levels in drugs were below WHO and Pharmacopeia (China) permitted levels. HI and HQ were below 1, indicating that risk linked to the metals were acceptable.
Article Information
42
1383-1392
587 KB
353
English
IJPSR
Kofi Sarpong, Emmanuel Agyapong Asare *, Emmanuel Dartey, Emmanuel Effah-Yeboah and Gadafi Iddrisu Balali
Department of Chemistry Education, College of Agriculture Education, Akenten Appiah-Menka University of Skills Training and Entrepreneurial Development, Mampong-Ashanti, Ghana.
kwakuasareagyapong@yahoo.com
03 June 2021
09 September 2021
17 February 2022
10.13040/IJPSR.0975-8232.13(3).1383-92
01 March 2022
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