ETHNO PHARMACOLOGICAL AND PHYTO PHARMACOLOGICAL PERCEPTION ON KALANCHOE (CRASSULACEAE) – A COMPREHENSIVE REVIEW

Natural molecules from plants are vital sources to explore potent lead molecules in the drug discovery process. Plants as A source of medicine is an ancient practice in India. The Indian subcontinent is a wide repository of medicinal plants that are being used in the traditional system of medicines. Kalanchoe is one of the medicinal plants; the succulent leaf juice is prepared by grinding the leaves mechanically and is a Tyler-made medicine being prescribed by traditional practitioners to combat various diseases and disorders. Various species of Kalanchoe find an important place in traditional medicine across the globe. This review article is a systematic compilation of recent updates on the worldwide ethnopharmacological uses and phytomolecules as therapeutic markers, pharmacological profiles, pharmacokinetic studies and SAR of bufadienolides from varied species of Kalanchoe. The systematic compilation of review articles will direct the scientific community to focus their research by doing further molecular and targeted throughput screening of the lead molecules from Kalanchoe, results in drug discovery from the potent herbal plant Kalanchoe. In addition, the unveiled tylor made medicine from ethnic herb Kalanchoe is substantiated by the scientific studies gives the scientific validation of folklore claims of Kalanchoe.