FORMULATION AND EVALUATION OF ANTIBACTERIAL GEL CONTAINING ETHANOL EXTRACT OF THORNS OF BOMBAX CEIBA
AbstractPurpose: Formulation and evaluation of the herbal gel preparation from the thorn’s extract of Bombax ceiba to check its antibacterial activity against the bacteria Staphylococcus aureus and Propionibacterium acnes Methods: Agar well diffusion method was employed for this purpose. Results: Gel formulation of different concentrations of extract were formulated that is 2%, 4%, 6%, and 8%, respectively, and antibacterial activity of the gels was measured against the bacteria Staphylococcus aureus and Propionibacterium acnes. In this clindamycin gel was used as the standard for comparative analysis. From evaluation results, it was concluded that the formulation of 8% showed better antibacterial activity as compared to other formulated preparations. In addition to this, an evaluation of gel formulations was performed considering various parameters, which were pH, appearance, viscosity, spreadability and homogeneity and the result were calculated. Conclusion: The ethanol thorn’ extract of Bombax ceiba possesses good antibacterial properties against the Staphylococcus aureus and Propionibacterium acnes. It also contains various phytoconstituents, which may be helpful in various health-related problems.
Article Information
43
4199-4204
918 KB
548
English
IJPSR
Prashant Chauhan * and Monika
Pharmacy Institute, Noida Institute of Engineering and Technology, 19, Knowledge Park-Ii, Institutional Area, Greater Noida, Uttar Pradesh, India.
chauhanprash8@gmail.com
13 February 2022
25 March 2022
24 April 2022
10.13040/IJPSR.0975-8232.13(10).4199-04
01 October 2022
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