AN INSIGHT INTO NEUROPATHIC PAIN: A SYSTEMIC AND UP-TO-DATE REVIEW

Neuropathic pain is a chronic illness that originates when abnormal functioning in the nervous system is observed or if the nervous system, including peripheral nerves, spinal cords, and brain, is damaged or not working properly, and originating pain. Therefore, it can be said that neuropathic pain is a chronic illness that directly impacts a large number of patients, society, and healthcare systems all over the world. The prevalence of neuropathic pain is believed to be 7-8% in the general population, and it is supposed to rise in the future. The impact of neuropathic pain on older persons is significant. The medical practitioner faces a problem in reducing neuropathic pain symptoms and improving the patient’s quality of life. Older people are easily and badly affected by neuropathic pain and are more susceptible to specific adverse effects. Neuropathic pain is different from nociceptive pain, and there is a requirement for a different treatment strategy for neuropathic pain management. The present review article is based on a detailed literature survey on etiology, symptoms, disease progression, modern approaches to treating neuropathic pain, and the information about marketed drugs used for effective treatment. The recommendations of clinical practices for neuropathic pain are presented in this review and their utility in clinical practice. The outcome-based clinical data research is employed for managing neuropathic pain and mitigating the associated conditions.