ANTIBACTERIAL ACTIVITY FROM DIFFERENT PARTS OF MORINGA OLEIFERA (L.) AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA

Antibacterial activity of methanolic extracts of different parts (leaves, flowers, green pods and roots) of Moringa oleifera plant were evaluated against gram positive bacteria Bacillus subtilis (Bs), Staphylococcus aureus (Sa) and gram negative bacteria Klebsiella pneumonia (Kp), Escherichia coli (Ec), Pseudomonas aeruginosa (Pa). The activities were performed by the agar well diffusion and cup plate method, with methanol as the negative and tetracycline as a positive control. Secondary metabolites extracted from all the parts of M. oleifera were found active against bacteria. Furthermore, the antimicrobial activity of the mentioned plant extracts was also examined against various gram-positive and gram-negative bacterial strains. It was observed that against K. pneumonia, leaves extracts (17.6 mm) of M. oleifera possess higher antibacterial activity as compared to others, flower extract (19.2mm) against B. subtilis, leaves extracts (22.6 mm) more effective against E. coli, pod extracts (22.5 mm) against S. aureus and leaf extract (21.9 mm) showed against P. aeruginosa as compared to others. The results reveal that M. oleifera might be a potential source for the treatment of gram-positive and gram-negative bacteria.