A REVIEW ON PULSATILE DRUG DELIVERY SYSTEMS
AbstractIn present days, solid oral drug dosage forms are widely used and the largest part of the entire drug delivery system due to their more, easy preferable route of administration and improved patient convenience nature. Most of the oral drug delivery systems show a distinctive drug release pattern, and the drug concentration is maintained within the limit of the therapeutic range. With technological advancement, pulsatile medication delivery devices are becoming increasingly important and popular for controlled delivery systems based on drug design. It maintains the circadian rhythm of the disease conditions and reduces the side effects of the drug. So, the important action of pulsatile drug delivery systems is used to delivery the drug at right time, site or target, and quantity. The drug release follows the sigmoid al release pattern, characterized by a period of no release (lag time). These systems release or deliver the drug based on the pathophysiological need of the disease at a specific time. So, it improves the therapeutic efficacy, compliance of the patient and decreases dosing frequency.
Article Information
4
3246-3254
653 KB
466
English
IJPSR
P. SS. Prasanna Kumar * and L. Srinivas
Department of Pharmaceutics, GITAM School of Pharmacy, GITAM Deemed to be University, Rushikonda, Vishakhapatnam, Andhra Pradesh, India.
pssprasanna1@gmail.com
04 October 2022
25 November 2022
28 November 2022
10.13040/IJPSR.0975-8232.14(7).3246-54
01 July 2023
Download