DRUG DISCOVERY AND DEVELOPMENT: A BASIC APPROACH TO IMPROVE THE SUCCESS OF DRUG DISCOVERY
AbstractDrug discovery is a process that aims at identifying a compound therapeutically useful in curing and treating disease. This process involves the identification of candidates, synthesis, characterization, validation, optimization, screening, and assays for therapeutic efficacy. Once a compound has shown its significance in these investigations, it will initiate the drug development process earlier to clinical trials. The new drug development process must continue through several stages to make a safe, effective medicine that has approved all regulatory requirements. One overall theme of our article is that the process is sufficiently long, complex, and expensive, so many biological targets must be considered for every new medicine ultimately approved for clinical use, and new research tools may be needed to investigate each new target. From initial discovery to a marketable medicine is a long, challenging task. It takes about 12 – 15 years from discovery to the approved medication and requires an investment of about USD 1 billion. This article outlines the processes of new drug discovery and development.
Article Information
12
3314-3326
1874 KB
455
English
IJPSR
Tarang Varshney, Shaily Saini and Aafreen *
SRMS College of Engineering, Technology & Research Bareilly, Bareilly, Uttar Pradesh, India.
aafreen844796@gmail.com
19 October 2022
28 November 2022
30 November 2022
10.13040/IJPSR.0975-8232.14(7).3314-26
01 July 2023
Download