PHOSPHATIDYLCHOLINE: A REVOLUTION IN DRUG DELIVERY TECHNOLOGY
AbstractIn recent years Phosphatidylcholine has greatly impacted the drug delivery technology. The very first and most important advantage of phospholipid based vesicular system is the compatibility of phospholipids with membrane of human either internal membrane as well as skin (external membrane). For a drug to be absorbed and distributed into organs and tissues and eliminated from the body, it must pass through one or more biological membranes/ barriers at various locations. Such a movement of drug across the membrane is called as drug transport. For the drugs to be delivered to the body should cross the membranous barrier. Either it would be from oral route or topical/transdermal route. Therefore the phospholipid based carrier systems are of considerable interest in this era. A number of drug delivery systems are based entirely on Phosphatidylcholine such as Liposome, Ethosome, Phytosome, Transferosomes, and Nanocochelates.
Article Information
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1-12
406
1612
English
IJPSR
P. VERMA *, A. RAM, A. K. JHA, A. MISHRA, A. THAKUR
Shri Shankaracharya Institute of Pharmaceutical Science*, Bhilai (C.G.), India
parma_pharma@rediffmail.com
4 January, 2010
20 January, 2010
28 January, 2010
http://dx.doi.org/10.13040/IJPSR.0975-8232.1(2).1-12
01 February, 2010
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