BUCCAL FILM-BASED NOVEL DRUG DELIVERY SYSTEM: RECENT CONCEPTS AND APPLICATION PERSPECTIVES

To increase patient compliance, safety, and effectiveness, the need for the design and development of a new dosage form has arisen. Novel film technology like buccal film meets all these needs. The buccal film is inserted into the mouth and the medicine is then absorbed via the buccal mucosa. Compared to alternative buccal drug delivery systems such as wafers, lozenges, microparticles, gel and tablets, buccal film is a more appealing and acceptable dosage form due to its small size, dose and ease of administration. Because it avoids first-pass digestion, buccal film is a very efficient dose form that significantly boosts bioavailability. It is more practical than other forms of dosing because it sticks well to the buccal mucosa of the mouth. Not ingesting the medicine is necessary; it is non-irritating and cost-efficient; other benefits include its sleek design, ease of use and biodegradability. Therefore, this dose type is preferred by both elderly and young patients. This review focuses on buccoadhesive drug delivery methods, which are reliant on adhering to mucus-coated biological surfaces. There is now a need for further investigation on topics like patient convenience and compliance. This article thoroughly analyzes buccal film, including its uses, drawbacks and advantages, methods of production, assessment criteria and formulation.