Posted by admin on Jan 31, 2022 in |
Marine environment is an exceptional storehouse of novel bioactive natural products that are mainly found in invertebrates such as sponges, arthropods, annelids, molluscs, etc. This diversity has been the source of unique chemical compounds. A large portion of these natural compounds has been extracted from marine invertebrates. Marine invertebrates are rich sources of bioactive compounds and their biotechnological potential attracts scientific and economic interest worldwide. Marine invertebrates are extremely diverse, largely productive, untapped oceanic resources with chemically unique bioactive compounds. Marine natural products are generally secondary metabolites. The number of natural products isolated from marine organisms increases rapidly. Isolated compounds from marine invertebrates have been shown pharmacological activities. They are helpful for the invention and discovery of bioactive compounds, primarily for deadly diseases like cancer, an Acquired immunodeficiency syndrome (AIDS), osteoporosis and so forth. So marine life is fascinating and has great potential for the development of drugs. The present review aims to know about the bioactive compounds produced by marine invertebrates and their use and application in the...
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Posted by admin on Jan 31, 2022 in |
The term “Naturals are the safer” is quite trendy, but the incomplete knowledge of the natural herbs interaction may result in several allergies and unwanted effects that may even take life and sometimes be critical to a life-threatening extent. The responsibility of the FDA is to ensure that the safety and efficacy of the drug consumed by humans and veterinary should be worthful and should cause no harm to their life. FDA also plays a vital role in the protection of public health by ensuring the effectiveness of the biological product and medical devices. Still, FDA does not show the same concern and guidelines for the efficacy and safety studies used for the common prescribed herbal drugs, dietary supplements, and marketing in the public domain. AS the favorability and likeliness of patients are inclining towards herbal remedies, there is increased production of such products. While manufacturing these products, the producers cannot submit the proof of safety and efficacy laid by the USFDA guidelines to the FDA before marketing. This...
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Posted by admin on Jan 31, 2022 in |
Depression is a significant contributor to the global burden of disease and affects people in all communities across the world. Today, depression is estimated to affect 350 million people. The World Mental Health Survey conducted in 17 countries found that, on average, about 1 in 20 people reported having an episode of depression in the previous year. Depressive disorders often start at a young age; they reduce people’s functioning and often are recurring. For these reasons, depression is the leading cause of disability worldwide in terms of the total years lost due to disability. Depression is known with some signs, such AS altered cognitive functions and mood, and is linked with a significant social dysfunction such as decreased quality of life. The demand for curbing depression and other mental health conditions is on the rise globally. A recent World Health Assembly called on the World Health Organization and its member states to take action in this...
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Posted by admin on Jan 31, 2022 in |
Hoarding behavior is a normal phenomenon commonly observed in all corners of the world to prevent future scarcity of resources and overcome challenges of survival. Hoarding signs typically develop in childhood or early adolescence, which may become a serious disorder in the late phase of life. At present, hoarding disorder has been covered under the chapter of ‘Obsessive-Compulsive and Related Disorders’ along with obsessive-compulsive disorder, body dysmorphic disorder, trichotillomania (hair-pulling disorder), and excoriation (skin-picking) disorder as per DSM-5. Hoarding disorder (HD) is defined as a persistent difficulty discarding possessions, resulting in an accumulation of belongings, causing severe clutter and the congestion of living areas. HD appears to be a chronic problem that presents a burden on family and society. Pharmacotherapy of this disorder exhibits a gloomy picture since no approved allopathic medicines are available for its management. The best clinically proven way to manage hoarding disorder is with cognitive behavioral therapy, which motivates the patient specifically in addressing the key characteristics of this disorder. Recent lines of evidence suggest...
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Posted by admin on Jan 31, 2022 in |
Karnataka is a southern state of India with richer diversity of plants and nearly 20% of its land area occupied by forest. Geographically Karnataka state is divided into three major zones, Western Ghats (Sahyadri), Coastal region and the Eastern plains which harbor a diversity of medicinal plants that have been used in traditional medicine by tribes and various ethnic groups for their primary health care systems. Effective herbal folk therapy is a challenge as it requires the knowledge of plants, method of collection, mode of preparation, dosage and many other aspects of treatment. Traditional uses of medicinal plants for neuro-musculo- skeletal disorders in Karnataka specifically have not been reviewed. This review presents the ethnomedicinal plants used for the treatment of common neuro-musculo-skeletal disorders such as arthritis, rheumatism, epilepsy, lumbago, paralysis, sprain, migraine, insomnia, depression, bone fracture, psychosis, anxiety, schizophrenia, bipolar disorder and neural disorders by various ethnic communities of Karnataka. A total 327 species of plants belonging to 93 families have been reviewed and compiled. 325 of them belong...
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